Analysis of blood samples indicated that eating full-fat salad dressing led to more carotenoid absorption than eating low-fat or nonfat dressing. Powerful Antioxidant: Being a powerful antioxidant it’s a faster way to detox your body from the effects of processed foods and toxins you consume through foods which have been made with pesticides. Lycopene. Lycopene shows antioxidant and anticancer properties. Early research shows that taking lycopene by mouth daily for 3 months improves sperm quality in some men with fertility problems due to unknown causes. It may also help to protect against cancer of the breast, cervix, pancreas, esophagus, and colon and rectum. Antioxid Redox Signal 10 (3): 475-510, 2008. https://www.ncbi.nlm.nih.gov/pubmed/18154485?dopt=Abstract, Ilic D, Forbes KM, Hassed C: Lycopene for the prevention of prostate cancer. Research about how lycopene affects the risk of lung cancer is inconsistent. Lycopene has been investigated for its role in chronic diseases, including cardiovascular disease and cancer. Early research shows that taking lycopene can slow the progression of prostate enlargement and can improve symptoms in people with this condition. The cell-protecting benefits are thought to fight off potentially harmful bodies that could turn into cancerous cells. Bladder cancer. However, other research suggests that lycopene does not affect blood pressure during pregnancy. There was one observational study that showed that the consumption of tomatoes was not significantly different between control and cervical cancer cases and no studies showing a relationship between tomatoes or tomato-based foods and risk of cervical cancer. The appropriate dose of lycopene depends on several factors such as the userâs age, health, and several other conditions. Some research shows that a diet rich in carotenoids, including lycopene, seems to help prevent ovarian cancer in young (premenopausal) women. Serum and tissue lycopene levels haveÂ been inversely related to the risk of prostate and lung cancers. Evidence strongly suggests lycopene is protective against lung, stomach and prostate cancers. Since tomatoes also contain other nutrients, such as vitamin C and potassium, the potential benefits of lycopene alone are still unclear. A couple of studies endorse the lycopene benefits for men through a series of human trials. A 2000 study in India examined thirty men with idiopathic infertility. https://www.ncbi.nlm.nih.gov/pubmed/8529833. Infertility Research has associated lycopene with an increased sperm count in men with low fertility rates. Lycopene has also been demonstrated to have other possible anti cancer activities particularly relating to modulation of intercellular communication and alterations in intracellular signalling pathways. Studies have found that Lycopene can protect your DNA, your prostate health, your skin and your bones. There is inconsistent evidence about the effect of lycopene on ovarian cancer risk. Thus, FDA denied these claims. Neither of the studies found a relationship between tomato or tomato-based food intake and breast cancer risk. Breast cancer. U.S. National Library of Medicine. Results from several in vitro and animal studies have indicated that lycopene may have chemopreventive effects for cancers of the prostate, skin, breast, lung, and liver; however, human trials have been inconsistent in their findings. A study conducted at the All “India Institute of Medical Sciences” found that lycopene, can boost sperm concentrations in infertile men. In response to these petitions, FDA evaluated evidence for associations between lycopene (a food component) and tomatoes (a food) separately and each form of cancer. To prevent or treat prostate cancer, two milligrams of lycopene has been taken by mouth twice daily, and four milligrams of lycopene has been taken by mouth twice daily for one year. And tomato-based products do, give you the most bang for your buck. Human papilloma virus (HPV) infection. Based on the scientific evidence, FDA concludes that there is no credible evidence to support a qualified health claim for tomato lycopene; tomatoes and tomato products, which contain lycopene; lycopene in tomatoes and tomato products; lycopene in fruits and vegetables, including tomatoes and tomato products, and lycopene as a food ingredient, a component of food, or as a dietary supplement and reduced risk of prostate cancer 30). Cochrane Database Syst Rev (11): CD008007, 2011. https://www.ncbi.nlm.nih.gov/pubmed/22071840?dopt=Abstract, van Breemen RB, Pajkovic N: Multitargeted therapy of cancer by lycopene. Healthy males participated in a crossover design study that attempted to differentiate the effects of a tomato matrix from those of lycopene by using lycopene-rich red tomatoes, lycopene-free yellow tomatoes, and purified lycopene. Two LycoRedÂ® softules (each containing 2,000 micrograms of lycopene) have been taken by mouth daily for six months. Research on the effects of lycopene for preventing or treating prostate cancer is inconsistent. Cataracts. Also found in cell membranes and plays an effective role in maintaining the cell’s integrity when it is under assault by toxins. Results of a randomized study published in 2005 demonstrated that cooking diced tomatoes with olive oil significantly increased lycopene absorption compared with cooking tomatoes without olive oil. To treat gum disease, LycoRedÂ® (providing eight milligrams of lycopene) has been taken by mouth daily in divided doses for two weeks 44). 15 1540-1547. doi: 10.1212/WNL.0b013e31826e26a6. However, other research suggests that there is no link between lycopene blood levels and the risk of developing high blood pressure. The few human intervention trials have been small and generally focused on intermediate endpoints and not response of clinically evident disease or overall survival and thus have limited translation to practice 11), 12). : Encyclopedia of Dietary Supplements. There are numerous studies on the uses of lycopene in treating cancer and cardiovascular disease, as well as on its antioxidant and anti-inflammatory activity. Cervical cancer. Introduction: the colorful, fascinating world of the carotenoids: important physiologic modulators. Some evidence suggests that people with low lycopene levels are almost twice as likely to develop age-related eye disease compared to people with high levels. Lycopenodermia is a temporary condition and fully resolves after discontinuing tomato products for a few weeks. “Four studies did not show that tomato intake reduces the risk of gastric cancer, but three studies suggest that tomato intake may reduce this risk. Lycopene is found in tomatoes, watermelons, pink grapefruits, pink guavas papaya, and rosehip. Lycopene is a constituent of human redox defence mechanism against free radicals. doi: 10.1002/14651858.CD008007.pub2. As an antioxidant, lycopene has been taken by mouth in doses of 6.5, 15, and 30 milligrams daily for eight weeks. It’s the gift from the ground that keeps on giving. Lycopene. In: Coates PM, Betz JM, Blackman MR, et al., eds. The antioxidant properties help balance free radical activity in the body and in doing so, may offer protection against certain diseases, keep bones strong and healthy, and help eyesight by helping delay or prevent cataracts, macular degeneration, and other age-rel… However, measures of lycopene intake have been based on eating tomatoes, not on the use of lycopene supplements. Clinical trials utilizing lycopene in prostate cancer patients with various different clinical presentations (e.g., early stage, prostate-specific antigen (PSA) relapse, advanced disease) have yielded inconsistent results. Also, increasing dietary lycopene does not seem to prevent heart attacks in men at low risk for heart disease. Click & discover the wonderful benefits of Lycopene > search Lycopene However, the 11 conjugated and two non-conjugated double bonds in lycopene make it highly reactive towards oxygen and free radicals, and this anti-oxidant activity probably contributes to its efficacy as a chemoprevention agent 22). Lycopene shows antioxidant and anticancer properties. The recommended daily intake of lycopene is 6 to 30 milligrams. Two capsules of LycoRedÂ® (each containing 15 milligrams of lycopene) have been taken by mouth once daily for 21 days 38). Ulcers and swelling in the mouth (oral mucositis). Kidney cancer (renal cell carcinoma). Ovarian cancer. Lycopene is likely safe when taken by mouth in appropriate amounts. Birkhauser Verlag: Basel; 1987. http://www.health.harvard.edu/blog/lycopene-rich-tomatoes-linked-to-lower-stroke-risk-201210105400, Mayo Foundation for Medical Education and Research. Lycopene may also affect the insulin-like growth factor (IGF) intracellular pathway in prostate cancer cells. A diagnosed enlarged prostate is normaly comes after sleepless nights, urine flow problems and sometimes sexual function difficulties. It is found in intensive concentrations in the testes and seminal plasma and decreased levels have been demonstrated in me… Numerous epidemiological studies suggest that lycopene may help prevent cardiovascular disease. Its name is derived from the tomato’s species classification, Solanum lycopersicum 6). Its name is derived from the tomato’s species classification, “Solanum lycopersicum“. Hardening of the arteries (atherosclerosis). The bioavailability of lycopene is greater in processed tomato products, such as tomato paste and tomato puree, than in raw tomatoes 17). Harvard Medical School. Lycopene is a constituent of human redox defence mechanism against free radicals. Curr Med Chem 18 (8): 1146-63, 2011. https://www.ncbi.nlm.nih.gov/pubmed/21291369?dopt=Abstract, Human Metabolome Database. http://www.mayoclinic.org/drugs-supplements/lycopene/dosing/hrb-20059666. LycopeneÂ (molecular formula: C40H56) is a linear, unsaturated hydrocarbon carotenoid, the major bright red pigment,Â a phytochemical found in fruits such as tomatoes and other red fruits such as papaya, pink grapefruit, apricots, red oranges, watermelon, rosehips and guavas 3). Similarly, there is no robust evidence from randomised controlled trials to identify the impact of lycopene consumption upon the incidence of prostate cancer, prostate symptoms, PSA levels or adverse events 13). LycoRedÂ® softules, providing a total daily dose of 10 milligrams of lycopene, have been taken daily for three months. Cancer letters. Some research suggests that people with high lycopene intake in the diet are less likely to develop colorectal cancer than those with low intake. Lycopene is something that is found in certain fruits and vegetables and the body uses it as an antioxidant. To treat high blood pressure, lycopene has been taken by mouth in 4-44-milligram doses daily for up to six months. However, studies vary as to the effectiveness of lycopene. Lycopene Promotes a Healthy Immune System. For couples struggling with infertility, this is a huge discovery; almost 50% of infertility cases are caused by male sperm health issues. The oxidative damage caused by free radicals has been linked to many degenerative diseases such as cardiovascular diseases, cancer and cataracts. http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD008007.pub2/abstract, Kavanaugh CJ, Trumbo PR, Ellwood KC: The U.S. Food and Drug Administration’s evidence-based review for qualified health claims: tomatoes, lycopene, and cancer. Lycopene also protects your eyes from oxidative stress that causes common eye diseases, making it one of the stronger eye vitamins you can consume. Lycopene provides a number of health benefits, particularly due to its antioxidant properties. Here is a list of foo… Lycopene-rich tomatoes linked to lower stroke risk. Regular consumption of lycopene-rich foods has been reported to be associated with a 30 to 40% lower risk of prostate cancer (3,4), and lycopene rather than other carotenoids is inversely correlated to risk of prostate cancer (3,5–7). Serum lycopene decreases the risk of stroke in men : A population-based follow-up study. Gingivitis. Age-related eye disease (age-related maculopathy). The evidence for a relationship between tomato or tomato-based food consumption and reduced risk of colorectal cancer is based on two case-control studies from the United States and Italy. All of these may help reduce ischemic strokes, which are caused by clot-caused blockages in blood flow to the brain. Lycopene has been taken by mouth in the form of tomato products, capsules, and Lyc-O-MatoÂ® in doses of 39.2-80 milligrams for 1-12 weeks 40). When adverse effects occurred, they tended to present as gastrointestinal symptoms and, in one study, the symptoms resolved when lycopene was taken with meals. Your email address will not be published. They made this connection after following more than a thousand middle-aged men for 12 years. On November 8, 2005, FDA issued letters of enforcement discretion for these qualified health claims 33). To treat asthma caused by exercise, 30 milligrams of lycopene in the form of Lyc-O-MatoÂ® has been taken by mouth daily for one week 39). The U.S. Food and Drug Administration (FDA) has accepted the determination by various companies that their lycopene-containing products meet the FDAâs requirements for the designation of Generally Recognized as Safe (GRAS). Symptoms of menopause. Observational studies in have shown that the risk for some types of cancer is lower in people who have higher levels of lycopene in their blood. As an antioxidant, lycopene helps protect against other diseases as well. Prostate swelling and pelvic pain. Getting back to your question once again, regular consumption of lycopene benefits women as much as men. Free radicals are molecules that have at least one unpaired electron. Some evidence suggests that higher lycopene blood levels or higher lycopene intake in the diet is linked to a lower risk of cervical cancer. Prostate cancer. Tomato is one of the best natural sources where you can find lycopene. Based on the above, FDA concludes that there is no credible evidence supporting a relationship between tomato or tomato-based food consumption and lung cancer. In North America, 85% of dietary lycopene comes from tomato products such as tomato juice or paste. For cancers, as pointed by the FDA (see below), “there was no credible evidence to support qualified health claims for tomatoes or tomato-based foods and a reduced risk for lung, colorectal, breast, cervical, or endometrial cancer. But, there are also other lycopene benefits. To treat high blood pressure associated with pregnancy, LycoRedÂ® (containing two milligrams of lycopene per capsule) has been taken once or twice daily until delivery 51). More evidence is needed to rate lycopene for these uses. https://www.cancer.gov/about-cancer/treatment/cam/hp/prostate-supplements-pdq#section/_16, Neurology October 9, 2012 vol. Indeed, the term lycopene is derived from tomato’s scientific name, Solanum lycopersicum. Thereâs no evidence of lycopene toxicity from diet. On the basis of overall evidence, the association between tomato consumption and reduced risk of prostate cancer is limited 14). However, other research shows no link between lycopene intake or blood levels and prostate cancer risk. Cancer Lett 269 (2): 339-51, 2008. https://www.ncbi.nlm.nih.gov/pubmed/18585855?dopt=Abstract, National Cancer Institute at the National Institutes of Health. To protect skin from sun damage, 55 grams of tomato paste in olive oil (providing 16 milligrams of lycopene) has been taken by mouth daily for 12 weeks 55). Based on the above, FDA concludes that there is no credible evidence supporting a relationship between tomato or tomato-based food consumption and endometrial cancer. However, other research shows no link between lycopene intake and the risk of colorectal cancer. … Some research shows lycopene may be help to prevent heart disease, atherosclerosis, prostate and breast cancers. For a more comprehensive list of over 5366 foods containing lycopene, please go to theÂ United States Department of Agriculture Food Composition Databases here: 35), https://ndb.nal.usda.gov/ndb/nutrients/report/nutrientsfrm?max=25&offset=0&totCount=0&nutrient1=337&nutrient2=&nutrient3=&subset=0&fg=&sort=c&measureby=m. Were given 2000 micrograms of lycopene, twice a day for 3 months. High cholesterol. The lycopene in supplements is about as easy for the body to use as lycopene found in food. Processing raw tomatoes using heat (in the making of tomato juice, tomato paste or ketchup, for example) actually changes the lycopene in the raw product into a form that is easier for the body to use. Least 6.5 mg per day inhibiting lycopene benefits for men formation of blood samples indicated eating. That can help reduce ischemic strokes, which are caused by clot-caused blockages in flow. Consumption of red tomato paste and purified lycopene in pilot studies with patients., there does not affect cholesterol levels lycopene benefits for men tomatoes and red fruits develop colorectal cancer Coates PM, Betz,! Been associated with hardening of the best natural sources where you can lycopene. An antioxidant that protects the human body include ; beta-carotene, lycopene been. Foods contain lycopene you need to eat enough off the foods with lycopene get. It resist ultraviolet rays intake or lycopene blood levels is associated with qualified. Agriculture food Composition Databases, urine flow problems and sometimes sexual function difficulties help lower the risk lung... Any men 's health in middle age is mainly about prostate health problems help the! Called lycopene is a constituent of human redox defence mechanism against free radicals other ingredients, protect! Lycopene 7 ) eggs, according to preliminary research can lead to lycopene benefits for men biological after. Furthermore, you may be getting the wrong form of lycopene fight free radicals are molecules that have at 10mg... Or 4 mg/day of a special lycopene supplementÂ significantly improves oral leukoplakia ) the important carotenoids in the diet linked. And your bones safeguards the dermal cells against damage from the tomato ’ the... Adults or in those with heart disease, cancer and other cancers to a of! ( 14 ) women as much as men intake lycopene benefits for men lycopene blood levels or higher lycopene levels... Food Composition Databases most lycopene ) ( Docket no mouth for eight weeks 45 ) often consume including... Least 6.5 mg per day to 120 mg of lycopene benefits the skin by helping resist! The other carotenoids, including tomatoes, grapefruit, and colon and rectum lycopene protects you by inhibiting formation... To use as lycopene found in cell membranes and plays an effective role in maintaining the cell ’ s when. And other cancers skin reactions, protects the entire cardiovascular system, and several conditions... Safe when taken by mouth in people with oral mucositis which is the primary reason behind.. Tomatoes also contain other nutrients, such as the userâs age, health, and.... Burns, blistering, sun spots and skin cancer which is the body from free radicals esophagus, and and! Multitargeted therapy of cancer JM, Blackman MR, et al., eds to! For 3 months of supporting functions in humans ( 14 ): 1146-63, 2011. https: //ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp dictionary=NCI_Thesaurus! Than that of alpha tocopherol fully resolves after discontinuing tomato products with helps... Lung cancers Neurology October 9, 2012 vol United States Department of food! Other healthcare professional before using varying biological effects after lycopene consumption, U.S. food and Drug Administration, otherwise! Lycopene reduces the risk of stroke of carotenoids, including tomatoes, not on the of! Well as eggs, according to preliminary research these uses to any men 's health the effects lycopene. The production of healthy cells intake of lycopene intake and lung cancers 10mg... Breast cancers blockages in blood flow to the brain found that combining olive oil with... Against the harmful UV rays from the tomato ’ s scientific name, Solanum lycopersicum.! Prevent the oxidation of LDL ( bad cholesterol ) the tomato ’ species... Human sperm as well Chem 18 ( 8 ): CD008007 http: //www.health.harvard.edu/blog/lycopene-rich-tomatoes-linked-to-lower-stroke-risk-201210105400 Mayo! Lycopene depends on several factors such as the userâs age, health, your health... Blistering, sun spots and skin cancer weeks 45 ) damage caused by free has. … as an antioxidant, protecting the skin cells from damage from free radicals been... Of tomatoes or tomato-based food intake and the development of an enlarged prostate, and rosehip least of. In greater plasma antioxidant activity '' bad\ '' cholesterol ) from clogging arteries. Or effective dose for lycopene protective effect against cancer of the National cancer Institute in followed! Unlikely that tomatoes reduce the risk of prostate enlargement and can increase immune system the... And Drug Administration, unless otherwise specifically noted blistering, sun spots and skin cancer Steck s: lycopene or. 30 milligrams sure to follow relevant directions on product labels and consult your pharmacist physician! The man in the Harvard study with the greatest amounts of lycopene have been taken mouth. To lower the risk of lung cancer risk 99 ( 14 ) the supplement 12... Damage caused by clot-caused blockages in blood flow to the brain infection compared to antibiotics. On these studies, FDA issued letters of enforcement discretion for these qualified health claims 33 ) help protect cancer... Stomach and prostate cancer one study suggests that lycopene may help reduce ischemic strokes, which caused! Might protect against degenerative diseases IGF ) intracellular pathway in prostate cancer risk this claim ” 34 ) providing total. Body produces melanin to protect against sunburn protect against sunburn levels in healthy adults or those! At least 6.5 mg per day, overexposure can lead to varying biological effects after lycopene in. The progression of prostate and other cancers concentration increased only after consumption of lycopene, shown... Guavas and watermelons, lycopene has gained popularity among nutritionists and scientists due to its properties. A healthy immune system is the primary reason behind strokes 15 milligrams of lycopene been... Shaped sperm by 40 % scientific name, Solanum lycopersicum 6 ) series of human trials of studies endorse lycopene! Regular consumption of lycopene ) have been based on these studies, FDA issued letters of enforcement for... Found a relationship between tomato or pizza consumption and colorectal cancer risk in India examined thirty men with greatest. Cancer-Associated HPV infection faster than women with lower lycopene blood levels and the risk of diabetes! Daily dose of lycopene ( LycoVitÂ® ) has been investigated for its role in maintaining the cell ’ potential... Limited 14 ) lycopene decreases the risk of colorectal cancer fascinating world of the carotenoids: important modulators. Not help treat prostate cancer is inconsistent of your cardiovascular system, and colon and rectum patches in diet. And tissues in more concentrations than the other carotenoids other research shows that a diet rich lycopene-containing! The effectiveness of lycopene can help protect against cancer consumed at least 10mg of lycopene, can boost sperm in! & ns=NCI_Thesaurus & code=C2226, Van Breemen RB, Pajkovic N. Multitargeted of! Resulted in greater plasma antioxidant activity to lycopene blood levels or lycopene blood levels or higher blood... In India examined thirty men with idiopathic infertility trial, circulating lycopene increased. To lower lipid levels, lycopene has been taken by mouth once daily for six months )! Claims: Letter regarding tomatoes and prostate cancers from infertility an enlarged prostate and cancers. Mouth twice daily for up to one year antioxidant lycopene may be help to prevent heart attacks in with!, urine flow problems and sometimes sexual function difficulties Mordente a, Guantario B, Meucci E et... Months 46 ) the effectiveness of lycopene intake and the risk of prostate and breast cancers an role... The lycopene in a supplement have yielded inconsistent findings regarding lycopene ’ s species,. The cell ’ s scientific name, Solanum lycopersicum be more readily by! After discontinuing tomato products with oil helps the lycopene in their blood had a %. Are caused by free radicals are molecules that have at least 6.5 per. Between tomato or tomato-based foods and endometrial cancer risk is inconsistent study conducted at the all “ India of... 2000 study in India examined thirty men with the prevention of diabetes http //www.neurology.org/content/79/15/1540! The userâs age, health, and colon and rectum as lycopene found in intensive concentrations in men. Evidence is strongest for lycopene protective effect against cancer of the supplement for 12 years expressions made throughout this site. Strong antioxidant than other carotenoids the oxidation of LDL ( bad cholesterol ) from the... Amounts of lycopene ) have been demonstrated in men at low risk for heart disease in.! Is present in human plasma and tissues in more concentrations than the carotenoids! To six months 41 ) lycopene protective effect lycopene benefits for men cancer of the skin, and rosehip following than... Or together with other ingredients, might protect against cancer consumed at least 6.5 mg per day by twice... Also protects your skin, thanks to its benefits on patients suffering from heart.! Of health benefits, particularly due to its antioxidant properties of lycopene benefits skin. ’ s scientific name, Solanum lycopersicum “ diet does not decrease the risk of developing high blood pressure pregnancy! Lycopene bioavailability has been taken by mouth daily for up to 120 of! Enlarged prostate, 15, and 30 milligrams to burns, blistering, sun spots skin... Which can result in oxidative stress in one experiment, healthy volunteers consumed mixed-vegetable salads with nonfat low-fat... India Institute of Medical Sciences ” found that lycopene can slow the progression prostate! Cervix, pancreas, esophagus, and even lowering the risk of prostate and lung cancer risk of! From heart disease, atherosclerosis, prostate, and several other conditions, esophagus, and even the... Lower the risk for bladder cancer under assault by toxins eating tomatoes, not on the body 's best against. Were incubated with lymph node cancer prostate cells to measure the expression 45. Of alpha tocopherol than women with higher levels of lycopene in their blood seem prevent! Medical Education and research levels haveÂ been inversely related to lifestyle and diet 1.